face_of_the_people_who_sank_all_their_money_into_the_fx_(meme)
(FX de Arigane Zenbu Tokasu/Tokashita Hito no Kao)
A meme originated from Ponoka-sempai's face in Ai Mai Mii.
A notable wall-eyed "derp face" with simple, thick-outlined, empty eyes and a small, open mouth.
The "FX" in question is the FOREX, or Foreign exchange market, which is often ridiculed in Japan (especially 2ch) as being a place for get-rich-quick schemes that often backfire.